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Gibco™ Human CCL3 (MIP-1 alpha) Recombinant Protein, PeproTech®
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Quantité:
1 mg
100 μg
20 μg
250 μg
5 μg
50 μg
500 μg
Conditionnement:
100µg
1mg
20µg
250µg
500µg
50µg
5µg
Description
Recombinant Human MIP-1alpha is a 7.8 kDa protein containing 70 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Both MIP-1alpha and MIP-1beta are structurally and functionally related CC chemokines. They participate in host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells (e.g. macrophages, lymphocytes and NK cells). While both MIP-1alpha and MIP-1beta exert similar effects on monocytes, their effect on lymphocytes differ; with MIP-1alpha selectively attracting CD8+ lymphocytes, and MIP-1beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1alpha and MIP-1beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1alpha and MIP-1beta are active on human and murine hematopoietic cells.
Spécification
Spécification
| Numéro d’adhésion | P10147 |
| À utiliser avec (application) | ELISA, Functional Assay, Western Blot |
| Formule | protein with no preservative |
| Identification génétique (Entrez) | 6348 |
| Poids moléculaire | 7.8 kDa |
| Nom | Human CCL3 (MIP-1 alpha) |
| Quantité | 5 μg |
| Source | E. coli |
| État réglementaire | RUO |
| Concentration en endotoxines | <1 EU/ μg |
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