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ACROBiosystems Human Osteoactivin / GPNMB Protein, His Tag
Description
Transmembrane glycoprotein NMB (GPNMB) is also known as Transmembrane glycoprotein HGFIN, DC-HIL and Osteoactivin (OA), which belongs to the PMEL/NMB family. GPNMB contains one PKD domain. GPNMB is a transmembrane glycoprotein that is up-regulated in various cancer cells, including in glioblastoma multiforme and is expressed in many melanoma cells, as well as in tissue macrophages. GPNMB protein acts as a downstream mediator of BMP-2 effects on osteoblast differentiation and function. GPNMB participates in bone mineralization, and functions as a negative regulator of inflammation in macrophages.
Spécification
Spécification
| Numéro d’adhésion | AAH32783 |
| Poids moléculaire | 53.4 kDa |
| Quantité | 1 mg |
| Source | Human Osteoactivin, His Tag (GPB-H5229) is expressed from human 293 cells (HEK293). It contains AA Ala 22 - Pro 486 (Accession # AAH32783). |
| Immunogène | Ala 22 - Pro 486 |
| Conditions de stockage | -20°C |
| Alias de gène | GPNMB,HGFIN,NMB,Osteoactivin |
| Nom usuel | Osteoactivin |
| Conjugué | Unconjugated |
| Espèces | Human |
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