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STEMCELL Technologies Human Recombinant CNTF
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Quantité:
10 μg
50 μg
Conditionnement:
10µg
Description
- Ciliary neurotrophic factor (CNTF) is a neurotrophic factor that belongs to the four-helix bundle cytokine family and is structurally related to interleukin 6 (IL-6), interleukin 11 (IL-11), leukemia inhibitory factor (LIF), and oncostatin M (OSM)
- CNTF binds to its receptor CNFTRα and induces formation of a heterodimer of the signal-transducing IL-6 receptor gp130 and LIF receptor (LIFR)-β, which triggers JAK/STAT, ERK, and the PI3K signaling cascades
- CNTF plays an important role in neurogenesis and the differentiation of neural stem cells and has been suggested to possess a therapeutic role in treating neurological disorders
- CNTF has also been shown to protect rod photoreceptors from light-induced damage and to have therapeutic effects on retinal degenerative diseases caused by genetic defects or damage induced by toxins, autoantibodies, or strong light
Spécification
Spécification
| Nom | Ciliary neurotrophic factor |
| Quantité | 10 μg |
| Type de cellule | Neural Cells, PSC-Derived; Neural Stem and Progenitor Cells; Neurons |
| Pureté ou qualité | ≥95% |
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