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Gibco™ Human TGF-alpha Recombinant Protein, PeproTech®
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Quantité:
1 mg
100 μg
20 μg
250 μg
500 μg
Conditionnement:
100µg
1mg
20µg
250µg
500µg
Description
Recombinant human TGF-alpha is a 50 amino acid polypeptide (5.5 kDa) which shares approximately 40% sequence homology with EGF, including 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
TGF-alpha is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-alpha induces anchorage-independence transformation in cultured cells. Human, murine and rat TGF-alpha are cross-species reactive. TGFalpha (aa 50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
Spécification
Spécification
| Numéro d’adhésion | P01135 |
| À utiliser avec (application) | ELISA, Functional Assay, Western Blot |
| Formule | protein with no preservative |
| Identification génétique (Entrez) | 7039 |
| Poids moléculaire | 5.5 kDa |
| Nom | Human TGF-alpha |
| Quantité | 100 μg |
| Source | E. coli |
| État réglementaire | RUO |
| Concentration en endotoxines | <1 EU/ μg |
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