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Gibco™ Human TRAIL Receptor-1 (soluble) Recombinant Protein, PeproTech®
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Quantité:
1 mg
10 μg
100 μg
250 μg
50 μg
500 μg
Conditionnement:
100µg
10µg
1mg
250µg
500µg
50µg
Description
Recombinant Human soluble TRAIL Receptor-1/DR4 is a 22.7 kDa protein (215 amino acid residues) consisting of the TNFR homologous, cysteine-rich portion of the extracellular domain. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
TRAIL-R1 (CD261, DR4) is a type I transmembrane protein, also called TRAIL receptor 1. The ligand for this DR4 death receptor has been identified and termed TRAIL, which is a member of the TNF family. DR4, as many other receptors (Fas, TNFR1, etc.), mediates apoptosis and NF kappaB activation in many cells and tissues. Apoptosis, a programmed cell death, is a operating process in normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by coupled of certain cytokines (TNF family - TNF, Fas ligand) and their death domain containing receptors (TNFR1, Fas receptor).
Spécification
Spécification
| Numéro d’adhésion | O00220 |
| À utiliser avec (application) | Functional Assay |
| Formule | protein with no preservative |
| Identification génétique (Entrez) | 8797 |
| Poids moléculaire | 22.7 kDa |
| Nom | Human TRAIL Receptor-1 (soluble) |
| Quantité | 100 μg |
| Source | E. coli |
| État réglementaire | RUO |
| Concentration en endotoxines | <1 EU/ μg |
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