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Gibco™ Human TWEAK, Animal-Free Recombinant Protein, PeproTech®
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Quantité:
1 mg
100 μg
25 μg
500 μg
Conditionnement:
100µg
1mg
25µg
500µg
Description
Recombinant Human TWEAK is a soluble 17.0 kDa polypeptide (154 amino acid residues) comprising the TNF-homologous region of TWEAK, and is generated by proteolytic processing of the full length membrane-anchored TWEAK protein. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
TNF-related weak inducer of apoptosis (TWEAK) is a member of the tumor necrosis factor superfamily (TNFSF) of structurally related cytokines. Like most other members of this family, TWEAK is a cell surface-associated type II transmembrane protein although a smaller, biologically active form can also be generated by cleavage near the cell membrane. TWEAK has multiple biological activities, including stimulation of cell growth and angiogenesis, induction of inflammatory cytokines, in addition to stimulation of apoptosis. The TWEAK signal transduction pathway has not been well established but it appears to signal via TweakR/Fn14 in a manner similar to that described for other TNFSF members that bind receptors lacking death domains.
Spécification
Spécification
| Numéro d’adhésion | O43508 |
| À utiliser avec (application) | Functional Assay |
| Formule | protein with no preservative |
| Identification génétique (Entrez) | 8742 |
| Poids moléculaire | 17 kDa |
| Nom | Human TWEAK, Animal-Free |
| Quantité | 25 μg |
| Source | E. coli |
| État réglementaire | RUO |
| Concentration en endotoxines | <0.1 EU/ μg |
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