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  4. Invitrogen™ Human MAP3K3 (MEKK3), GST Tag Recombinant Protein

Invitrogen™ Human MAP3K3 (MEKK3), GST Tag Recombinant Protein

Code produit. p-7121799
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Quantité:
1 mg
100 μg
Conditionnement:
100µg
1mg
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Code produit. 15498563

Marque: Invitrogen™ PR7352A

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Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length

MAP3K3 (MEKK3) directly regulates MAPK8 and extracellular signal-regulated protein kinase (ERK) pathways by phosphorylating multiple MAP2Ks. Northern blot analysis revealed a 4. 6-kb transcript that appears to be ubiquitously expressed. This protein directly regulates the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by activating SEK and MEK1/2 respectively; it does not regulate the p38 pathway. In cotransfection assays, it enhanced transcription from a nuclear factor kappa-B (NFKB)-dependent reporter gene, consistent with a role in the SAPK pathway. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
TRUSTED_SUSTAINABILITY

Specifications

Numéro d’adhésion Q99759
Concentration See Label
À utiliser avec (application) Kinase Assay
Formule 50 mM tris with 0.02% Triton X-100, 0.5 mM EDTA, 150 mM NaCl, 2 mM DTT, 50% glycerol and no preservative; pH 7.5
Identification génétique (Entrez) 4215
Poids moléculaire 99.8 kDa
Nom Human MAP3K3 (MEKK3), GST Tag
Quantité 100 μg
État réglementaire RUO - research use only
Alias de gène AW548911; MAP/ERK kinase kinase 3; MAP3K3; MAPK/ERK kinase kinase 3; MAPKKK3; MEK kinase 3; MEKK 3; Mekk3; mitogen activated protein kinase kinase kinase 3; mitogen-activated protein kinase kinase kinase 3; mKIAA4031
Nom usuel MEKK3
Famille des kinases STE11 Kinase Family
Conjugué Unconjugated
Espèces Human
Recombinant Recombinant
Marqueur de protéine GST-tag
Séquence Full length
Contenu et stockage -80°C, Avoid Freeze/Thaw Cycles
Système d’expression Insect cells
Forme Liquid
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