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ACROBiosystems Mouse BAFFR / TNFRSF13C Protein, Fc Tag

HPLC-verified

Marque:  ACROBiosystems BAR-M5259-1MG

Informations supplémentaires : Poids : 0.00001kg

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Code produit. 15876007

  • 2219.34€ / 1mg
Date d’expédition estimée: 07-01-2022

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Description

Description

BAFF receptor (B-cell activating factor receptor, BAFF-R), also known as tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), is a membrane protein of the TNF receptor superfamily which recognizes BAFF. B-cell activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of BAFF in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 33.3 kDa. As a result of glycosylation, the protein migrates as 40-45 kDa under reducing (R) condition, and 80-100 kDa under non-reducing (NR) condition (SDS-PA
Spécification

Spécification

NP_082351.1
HEK293
Mouse
33.3 kDa
1 mg
Ser 10 - Ala 71
BAFFR,TNFRSF13C,BROMIX,CD268,CVID4,prolixin,BAFF-R
Unconjugated
Tris with Glycine, Arginine and NaCl, pH7.5
Less than 1.0 EU / µg by the LAL method.
Other Recombinant Proteins
Powder
>95% as determined by SDS-PAGE
Mouse BAFFR, Fc Tag (BAR-M5259) is expressed from human 293 cells (HEK293). It contains AA Ser 10 - Ala 71 (Accession # NP_082351.1).
-20°C
BAFFR
Fc Tag
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