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ACROBiosystems Mouse Nectin-4 Protein, His Tag, low endotoxin

Marque:  ACROBiosystems NE4-M52Ha-1mg

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 17256340

  • 3512.64€ / 1mg
Expédition estimée: 14-10-2022
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Description

Description

Nectin-4 (gene name PVRL4, poliovirus receptor-like 4) is a 66 kDa type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. Nectins are cell adhesion molecules that play a key role in various biological processes such as polarity, proliferation, differentiation and migration, for epithelial, endothelial, immune and neuronal cells, during development and adult life. Nectin-4 is a tumor-associated antigen in 50%, 49% and 86%o of breast, ovarian and lung carcinomas, respectively, mostly on tumors of bad prognosis. Its expression is not detected in the corresponding normal tissues.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 36.2 kDa. The protein migrates as 38-43 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spécification

Spécification

NP_082169.2
>95% as determined by SDS-PAGE.
Mouse Nectin-4, His Tag (NE4-M52Ha) is expressed from human 293 cells (HEK293). It contains AA Gly 31 - Ser 347 (Accession # Q8R007-1).
-20°C
Nectin-4
His Tag
Less than 0.1 EU / µg by the LAL method.
Powder
Mouse
36.2 kDa
1 mg
Gly 31 - Ser 347
NECTIN4,LNIR, PRR4, PVRL4
Unconjugated
PBS, Arginine, pH7.4
HEK293
Immune Checkpoint Proteins
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FDS
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