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Invitrogen™ PIK3CA/PIK3R3 (p110 alpha /p55 gamma) Recombinant Human Protein
This PIK3CA/PIK3R3 (p110 alpha /p55 gamma) Recombinant Human Protein (full length) was expressed in insect cells.
Marque: Invitrogen™ A31082
Informations supplémentaires : Poids : 0.01000kg
Description
- This PIK3CA/PIK3R3 (p110 alpha /p55 gamma) recombinant human protein (full length) was expressed in insect cells
- PIK3CA/PIK3R3 lipid kinase (p110 alpha /p55 gamma), or Phosphatidylinositol 3-kinase (PIK3), phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position
- This serves as a second messenger in growth signaling pathways
- PIK3CA comprises a 110 kDa catalytic subunit and a regulatory subunit of either 85, 55, or 50 kDa
- PIK3CA plays an important role in the metabolic actions of insulin
- A mutation in the PIK3CA has been associated with insulin resistance and plays an important role in glucose homeostasis in vivo
- PIK3CA also plays an essential role in the development and induction of mast cells in normal and pathogenic immune responses
- PIK3CA/PIK3R3 (p110 alpha /p55 gamma) recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service
- Validated for use with the Adapta™ assay
- Available in multiple pack sizes for convenient use
Spécification
| PIK3CA: NP_006209.2, PIK3R3: AAH21622 | |
| 20 µg | |
| Full Length | |
| His Tag | |
| Dry Ice | |
| Full Length, Recombinant, Active | |
| Kinase Assay |
| 125.4/56.3 kDa | |
| PI3 Kinase | |
| Yes | |
| Storage Buffer: 50 mM sodium phosphate, pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.1 mM PMSF, 0.25 mM DTT, 25% glycerol. | |
| Insect | |
| Liquid | |
| Human |