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Invitrogen™ Human PIK3CA/PIK3R3 (p110 alpha/p55 gamma), His Tag Recombinant Protein

Human PIK3CA/PIK3R3 (p110 alpha/p55 gamma), His Tag Recombinant Protein

Marque:  Invitrogen™ A31082

Informations supplémentaires : Poids : 0.01000kg

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Code produit. 15980313

  • 852.00€ / 20µg
Expédition estimée: 22-04-2024
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Description

Description

  • This PIK3CA/PIK3R3 (p110 alpha /p55 gamma) recombinant human protein (full length) was expressed in insect cells
  • PIK3CA/PIK3R3 lipid kinase (p110 alpha /p55 gamma), or Phosphatidylinositol 3-kinase (PIK3), phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position
  • This serves as a second messenger in growth signaling pathways
  • PIK3CA comprises a 110 kDa catalytic subunit and a regulatory subunit of either 85, 55, or 50 kDa
  • PIK3CA plays an important role in the metabolic actions of insulin
  • A mutation in the PIK3CA has been associated with insulin resistance and plays an important role in glucose homeostasis in vivo
  • PIK3CA also plays an essential role in the development and induction of mast cells in normal and pathogenic immune responses
  • PIK3CA/PIK3R3 (p110 alpha /p55 gamma) recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service
  • Validated for use with the Adapta™ assay
  • Available in multiple pack sizes for convenient use
Spécification

Spécification

PIK3CA: NP_006209.2, PIK3R3: AAH21622
125.4/56.3 kDa
PI3 Kinase
Human
His Tag
Dry Ice
Full Length, Recombinant, Active
Kinase Assay
20 μg
Full Length
Recombinant
Storage Buffer: 50 mM sodium phosphate, pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.1 mM PMSF, 0.25 mM DTT, 25% glycerol.
Insect
Liquid
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