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Invitrogen™ Human RET, GST Tag Recombinant Protein
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Quantité:
10 μg
Conditionnement:
10µg
Description
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Cytoplasmic.
The receptor tyrosine kinase RET is a member of the cadherin superfamily. RET plays a crucial role in neural crest development, and can undergo oncogenic activation by cytogenetic rearrangement. RET transduce signals for cell growth and differentiation. Mutations in the RET gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for the RET gene. Additional transcript variants have been described for RET but their biological validity has not been confirmed.
Spécification
Spécification
| Numéro d’adhésion | P07949 |
| Concentration | See Label |
| À utiliser avec (application) | Kinase Assay |
| Formule | 50mM tris HCl with 2mM DTT, 150mM NaCl, 50% glycerol, 0.5mM EDTA, 0.02% Triton X-100 and no preservative; pH 7.5 |
| Identification génétique (Entrez) | 5979 |
| Poids moléculaire | 79 kDa |
| Nom | Human RET, GST Tag |
| Plage de pH | 7.5 |
| Méthode de purification | Purified |
| Quantité | 10 μg |
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