missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Réactifs pour l’analyse des protéines
  4. Petites molécules bioactives
  5. Tocris Bioscience™ Y-27632 dihydrochloride

Tocris Bioscience™ Y-27632 dihydrochloride
GREENER_CHOICE

Code produit. p-4785795
Click to view available options
Quantité:
1 mg
10 mg
50 mg
Conditionnement:
10mg
1mg
50mg
Les retours ne sont pas autorisés pour ce produit. Afficher la politique du retour.

Code produit. 30001217

Marque: Tocris Bioscience™ 1254/1

Veuillez vous pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant!

Les retours ne sont pas autorisés pour ce produit. Afficher la politique du retour.

Description

Selective p160ROCK inhibitor

Y-27632 dihydrochloride is a selective ROCK inhibitor (Ki values are 0.14-0.22, 0.3, 25, 26 and > 250 μM for ROCK1 (p160 ROCK), ROCK2, PKA, PKC and MLCK respectively). Also inhibits PRK2 (IC50 = 600 nM). Increases survival rate of human embryonic stem (hES) cells and iPSC undergoing cryopreservation. Used in combination with CHIR99021, RepSox, Forskolin, SP 600125, Go 6983 and VPA to reprogram fibroblasts to mature neurons. Also optimizes naive human pluripotent stem cell growth and viability following naive cell derivation from primed ESCs and iPSCs using naive human stem cell medium (NHSM). Used as component of growth media for urothelial organoids. Cell-permeable, orally bioavailable and active in vivo. Y-27632 synthesized to cGMP guidelines also available.

For more information about how Y-27632 dihydrochloride may be used, see our protocols: Transdifferentiating Fibroblasts into Neurons, Converting Fibroblasts into Cardiomyocytes (9C Cocktail), Accelerated Induction of Cortical Neurons from hiPSCs, Human iPSC-derived Myoblasts .

TRUSTED_SUSTAINABILITY

Identifiants chimiques

CAS 129830-38-2
Formule moléculaire C14H23Cl2N3O

Spécification

Nom chimique ou matériau Y-27632 dihydrochloride
Quantité 1 mg
Poids de la formule 320.26
Pureté >98%
Poids moléculaire 320.258
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.