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  6. 9-bêta-D-arabinofuranosyladénine, 99 %, Thermo Scientific Chemicals

9-bêta-D-arabinofuranosyladénine, 99 %, Thermo Scientific Chemicals

Code produit. 15466709
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Quantité:
1 g
5 g
25 g
Unit Size:
1g
25g
5g
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Product Code. 15466709

Brand: Thermo Scientific Alfa Aesar J65076.06

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Description

CAS: 5536-17-4 | C10H13N5O4 | 267.25 g/mol

Vidarabine is a neurotransmitter that acts as the preferred endogenous agonist at all adenosine receptor subtypes. Vidarabine is an inhibitor of A cyclase and DNA Polymerase. Used to study the roles of AMP-activated protein kinase (AMPK) in cell signaling. Cell-permeable adenylate cyclase inhibitor; in detergent-dispersed rat brain preparation, IC50 = 30 ?M. Clinically significant antiviral agent, especially against herpes simplex (HSV),1 by inhibition of DNA polymerase.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
La vidarabine est un neurotransmetteur qui agit comme l’agoniste endogène préféré de tous les sous-types de récepteurs d’adénosine. La vidarabine est un inhibiteur de la cyclase A et de l’ADN polymérase. Utilisé pour étudier les rôles de la protéine kinase activée par l’AMP (AMPK) dans la signalisation cellulaire. Inhibiteur d’adénylate cyclase perméable aux cellules ; dans la préparation du cerveau de rat dispersée par le détergent, IC50 = 30 μM. Agent antiviral cliniquement significatif, en particulier contre l’herpès simplex (HSV),1 par inhibition de l’ADN polymérase.

Solubilité
Soluble dans le DMF (10 mg/ml), 0,5 M HCl (50 mg/ml), le DMSO (53 mg/ml à 25°C), l’éthanol (<1mg/mL at 25°C), and water (3 mg/ml at 25°C).

Remarques
Garder le récipient hermétiquement fermé. Conserver à l’abri des oxydants.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 5536-17-4
Formule moléculaire C10H13N5O4
Poids moléculaire (g/mol) 267.25
Numéro MDL MFCD00065471,MFCD00065471,MFCD00475667,MFCD00005752,MFCD00065471
Clé InChI OIRDTQYFTABQOQ-UHFFFAOYNA-N
Synonyme 3s,4r,5r-2-6-aminopurin-9-yl-5-hydroxymethyl oxolane-3,4-diol, prestwick_983, 9-lyxofuranosyladenine
CID PubChem 6420052
Nom IUPAC (3S,4R,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diole
SMILES NC1=C2N=CN(C3OC(CO)C(O)C3O)C2=NC=N1

Specifications

Nom chimique ou matériau 9-beta-D-Arabinofuranosyladenine
Couleur Blanc
Quantité 5 g
Beilstein 624881
Merck Index 14,9976
Informations sur la solubilité Soluble in DMF (10mg/ml),0.5 M HCl (50mg/ml),DMSO (53mg/ml at 25°C),ethanol (<1mg/ml at 25°C),and water (3mg/ml at 25°C).
Poids de la formule 267.24
Pourcentage de pureté 99%
Forme physique Poudre

RUO - Usage exclusivement réservé à la recherche

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