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Invitrogen™ AHA1 Polyclonal Antibody
Description
Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji. Predicted reactivity: Mouse (94%), Rat (93%), Rhesus Monkey (100%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Acts as a co-chaperone of HSP90AA1 (PubMed:29127155). Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity (PubMed:29127155). Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:27353360). Competes with the inhibitory co-chaperone TSC1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:29127155). [UniProt].
Spécification
Spécification
| Antigène | AHA1 |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.98 mg/mL |
| Conjugué | Unconjugated |
| Formule | 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7 |
| Expression | Ahsa1 |
| Numéro d’ordre du gène | O95433, Q8BK64 |
| Alias de gène | Activator of 90 kDa heat shock protein ATPase homolog 1; activator of Hsp90 ATPase activity 1; Activator of Hsp90 ATPase protein 1; Aha 1; AHA1; AHA1, activator of heat shock 90kDa protein ATPase homolog 1; AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast); AHA1, activator of heat shock protein ATPase 1; AHA1, activator of heat shock protein ATPase homolog 1; Aha1p; AHSA 1; Ahsa1; BC023857; C14orf3; hAha1; Hsp90 co-chaperone AHA1; HSPC322; p38; SHSA1; YD8142.16; YD8142B.06; YDR214W |
| Symboles de gène(s) | Ahsa1 |
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Nom du produit
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