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Description
The 2.4G2 antibody reacts specifically with a common nonpolymorphic epitope on the extracellular domains of the mouse Fc γ III and Fc γ II receptors. It has also been reported to bind the Fc γ I receptor (CD64) via its Fc domain. 2.4G2 mAb blocks non-antigen-specific binding of immunoglobulins to the Fc γ III and Fc γ II, and possibly Fc γ I, receptors in vitro and in vivo . CD16 and/or CD32 are expressed on natural killer cells, monocytes, macrophages, dendritic cells (at low levels), Kupffer cells, granulocytes, mast cells, B lymphocytes, immature thymocytes, and some activated mature T lymphocytes.
Spécification
| CD16/CD32 | |
| Monoclonal | |
| 0.5mg/mL | |
| FcγRIII/FcγRII; Fcgr3/Fcgr2 | |
| Rat | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C |
| Blocking Assay, Flow Cytometry | |
| 2.4G2 | |
| Unconjugated | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| Mouse BALB/c Macrophage J774 Cell Line | |
| 0.5 mg | |
| Immunology | |
| Mouse | |
| IgG2b κ |
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Nom du produit
For Research Use Only.
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