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  6. Cyclin B1 Mouse, Unlabeled, Clone: GNS-1, BD

Cyclin B1 Mouse, Unlabeled, Clone: GNS-1, BD

Code produit 15887598
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Quantité:
0.1 mg
0.25 mg
Conditionnement:
1 pièce
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15887598 0.1 mg 1 pièce
15897598 0.25 mg 1 pièce
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Code produit 15887598 Fournisseur BD Biosciences Code fournisseur 554176

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Description

Mouse Monoclonal Antibody

Cyclins and cyclin-dependent kinases (cdks) are evolutionarily conserved proteins that are essential for cell-cycle control in eukaryotes. Cyclins (regulatory subunits) bind to cdks (catlytic subunits) to form complexes that regulate the progression of the cell cycle. The main cyclin-cdks complexes formed in vertebrate cells are cyclin D-cdk4 (G0/G1), cyclin E-cdk2 (G1/S), cyclin A-cdk2 (S) and cyclin B1-cdk1 (G2/M). These complexes are regulated by activating and inhibitory phosphorylation events, as well as by interactions with small regulatory proteins, such as p21 and p27 [Kip1]. Cyclin B1 is a mitotic cyclin, where expression is normally low in G0/G1, increases in S and is maximal during the G2/M phase. Cyclin B1 is rapidly degraded at the end of mitosis, and is required for cells to exit from mitosis. This antibody has been reported to react to hamster and mouse cyclin B1. In addition, the GNS-1 antibody has been reported to recognize an epitope between amino acids 1-21 of human cyclin B1.

Host Species: Mouse
Clone: GNS-1
Isotype: IgG1
Species Reactivity: Human
Immunogen: Human Cyclin B1 Recombinant Protein
Formula Weight [Chemical]: 62kDa

Bioimaging, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blotting

TRUSTED_SUSTAINABILITY

Spécification

Antigène Cyclin B1
Applications Western Blot
Classification Monoclonal
Clone GNS-1
Concentration 0.5mg/mL
Conjugué Unconjugated
Formule Aqueous buffered solution containing ≤0.09% sodium azide.
Espèces hôtes Mouse
Immunogène Human Cyclin B1 Recombinant Protein
Méthode de purification Affinity Purified
Quantité 0.1 mg
État réglementaire RUO
Disciplines de recherche Cell Biology
Primaire ou secondaire Primary
Espèces cibles Hamster, Human, Mouse
Contenu et stockage Store undiluted at 4°C
Isotype IgG1
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For Research Use Only.

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