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  6. TRADD Mouse, Unlabeled, Clone: 37, BD

TRADD Mouse, Unlabeled, Clone: 37, BD

Artikelnummer. p-3855764
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Quantité:
150 μg
50 μg
Pakningsstørrelse:
1 kit
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Artikelnummer. Quantité unitSize
15835529 50 μg 1 kit
15845529 150 μg 1 kit
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Artikelnummer. 15835529 Leverandør BD Biosciences Leverandørnr. 610572

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Beskrivelse

Mouse Monoclonal Antibody

TNFα (Tumor Necrosis Factor) stimulates programmed cell death and NF-κB activation as a result of its binding to the TNF receptor 1 (TNFR1). Within this receptor, a sequence referred to as the “death domain” has been shown to be necessary for both of these functions. Using the yeast two-hybrid system to detect proteins which interact with the receptor through this “death domain”, a 34kDa protein was found and designated TRADD (TNFR1-Associated Death Domain protein). TRADD appears to contain no intrinsic catalytic activity. It also contains a death domain and it has been shown to bind to FADD and RIP. Mutational analysis of TRADD demonstrates that programmed cell death and NF-κB activation are distinct and controlled independently.

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

TRUSTED_SUSTAINABILITY

Tekniske data

Antigène TRADD
Applications Western Blot
Classification Monoclonal
Clone 37
Concentration 250μg/mL
Conjugué Unconjugated
Description TNFR1-Associated Death Domain protein
Formule Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Espèces hôtes Mouse
Immunogène Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Méthode de purification Affinity Purified
Quantité 50 μg
État réglementaire RUO
Disciplines de recherche Cell Biology
Primaire ou secondaire Primary
Espèces cibles Human, Rat
Contenu et stockage Store undiluted at -20°C.
Isotype IgG1
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For Research Use Only.

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