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ACROBiosystems Biotinylated Human B7-H3 / CD276 Protein, Avitag™,His Tag

Biotinylated Protein

Marque:  ACROBiosystems B73-H82E6-200UG

Informations supplémentaires : Poids : 0.00001kg

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Code produit. 15845957

  • 1943.44€ / 200µg
Expédition estimée: 08-02-2023
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Description

Description

B7 homolog 3 (B7-H3), a member of the immunoglobulin superfamily, is also known CD276, which contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domains. B7-H3 may participate in the regulation of T-cell-mediated immune response. B7-H3 also plays a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. Furthermore, B7-H3 is involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. It could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy.

This protein carries an Avi tag (Avitag™) at the C-terminus, followed by a polyhistidine tag. The protein has a calculated MW of 26.5 kDa. The protein migrates as 35-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spécification

Spécification

NP_079516.1
26.5 kDa
200 µg
Leu 29 - Pro 245
B7-H3,CD276,B7 homolog 3
Precision Avi
PBS, pH7.4
HEK293
Human
Powder
>95% as determined by SDS-PAGE
Biotinylated Human B7-H3, Avitag,His Tag (B73-H82E6) is expressed from human 293 cells (HEK293). It contains AA Leu 29 - Pro 245 (Accession # Q5ZPR3-2).
-20°C
B7-H3
His Tag and Avi Tag
Less than 1.0 EU / µg by the LAL method.
MABSol™ Biotin Labeled Proteins
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