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ACROBiosystems Biotinylated Human CD4 Protein, His, Avitag™

Biotinylated Protein

Marque:  ACROBiosystems CD4-H82E8-25UG

Informations supplémentaires : Poids : 0.00001kg

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Code produit. 15846197

  • 431.88€ / 25µg
Expédition estimée: 14-02-2023
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Description

Description

T-cell surface glycoprotein CD4 is also known as T-cell surface antigen T4/Leu-3. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is accessory protein for MHC class-II antigen/T-cell receptor interaction. CD4 induces the aggregation of lipid rafts. CD4 is a primary receptor used by HIV-1 to gain entry into host T cells. HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors. Therefore, medical professionals refer to the CD4 count to decide when to begin treatment for HIV-infected patients.

This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag. The protein has a calculated MW of 45.0 kDa. The protein migrates as 55-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spécification

Spécification

NP_000607.1
45.0 kDa
25 µg
Lys 26 - Pro 396
CD4,CD4mut,LEU3
Precision Avi
PBS, pH7.4
HEK293
Human
Powder
>95% as determined by SDS-PAGE
Biotinylated Human CD4, His,Avitag (CD4-H82E8) is expressed from human 293 cells (HEK293). It contains AA Lys 26 - Pro 396 (Accession # P01730-1).
-20°C
CD4
His Tag and Avi Tag
Less than 1.0 EU / µg by the LAL method.
MABSol™ Biotin Labeled Proteins
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