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ACROBiosystems Biotinylated Human GITR Ligand / TNFSF18 Protein, Avitag™,Fc Tag

Biotinylated Protein

Marque:  ACROBiosystems GIL-H82F8-25UG

Informations supplémentaires : Poids : 0.00001kg

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Code produit. 15866837

  • 353.08€ / 25µg
Date d’expédition estimée: 29-12-2021

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Description

Description

Tumor necrosis factor ligand superfamily member 18 (TNFSF18) is also known as Glucocorticoid - induced TNF-related ligand (GITRL or GITR Ligand), Activation - inducible TNF - related ligand (AITRL), which belongs to the tumor necrosis factor family. TNFSF18 is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 / GITRL is up-regulated after stimulation by bacterial lipopolysaccharides (LPS). TNFSF18 Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. TNFSF18 / GITR Ligand is important for interactions between activated T-lymphocytes and endothelial cells. TNFSF18 also mediates activation of NF-kappa-B.

This protein carries an Avi tag (Avitag™) at the N-terminus, followed by a human IgG1 Fc tag. The protein has a calculated MW of 43.5 kDa. The protein migrates as 45-53 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spécification

Spécification

NP_005083.2
HEK293
Human
43.5 kDa
25 µg
Gln 50 - Ser 177
TNFSF18,AITRL,TL6,hGITRL,GITR Ligand
Precision Avi
Tris with Glycine, Arginine and NaCl, pH7.5
Less than 1.0 EU / µg by the LAL method.
MABSol™ Biotin Labeled Proteins
Powder
>90% as determined by SDS-PAGE
Biotinylated Human GITR Ligand, Avitag,Fc Tag (GIL-H82F8) is expressed from human 293 cells (HEK293). It contains AA Gln 50 - Ser 177 (Accession # AAH69319.1).
-20°C
GITR Ligand
Avi Tag and Fc Tag
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