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ACROBiosystems Biotinylated Human GITR Ligand / TNFSF18 Protein, Avitag™,Fc Tag
Biotinylated Protein
Marque: ACROBiosystems GIL-H82F8-25UG
Informations supplémentaires : Poids : 0.00001kg
Description
Tumor necrosis factor ligand superfamily member 18 (TNFSF18) is also known as Glucocorticoid - induced TNF-related ligand (GITRL or GITR Ligand), Activation - inducible TNF - related ligand (AITRL), which belongs to the tumor necrosis factor family. TNFSF18 is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 / GITRL is up-regulated after stimulation by bacterial lipopolysaccharides (LPS). TNFSF18 Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. TNFSF18 / GITR Ligand is important for interactions between activated T-lymphocytes and endothelial cells. TNFSF18 also mediates activation of NF-kappa-B.
This protein carries an Avi tag (Avitag™) at the N-terminus, followed by a human IgG1 Fc tag. The protein has a calculated MW of 43.5 kDa. The protein migrates as 45-53 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spécification
NP_005083.2 | |
25 μg | |
Gln 50 - Ser 177 | |
TNFSF18,AITRL,TL6,hGITRL,GITR Ligand | |
Precision Avi | |
Avi Tag and Fc Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>90% as determined by SDS-PAGE |
43.5 kDa | |
Biotinylated Human GITR Ligand, Avitag,Fc Tag (GIL-H82F8) is expressed from human 293 cells (HEK293). It contains AA Gln 50 - Ser 177 (Accession # AAH69319.1). | |
-20°C | |
GITR Ligand | |
Human | |
Tris with Glycine, Arginine and NaCl, pH7.5 | |
HEK293 | |
MABSol™ Biotin Labeled Proteins |