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ACROBiosystems Biotinylated Human LILRA3 / CD85e Protein, His, Avitag™

Biotinylated Protein

Marque:  ACROBiosystems LI3-H82E0-200UG

Informations supplémentaires : Poids : 0.00001kg

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Code produit. 15877257

  • 1392.13€ / 200µg
Date d’expédition estimée: 29-12-2021

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Description

Description

Leukocyte immunoglobulin-like receptor subfamily A member 3 (LILRA3) is also known as CD85 antigen-like family member E (CD85e), immunoglobulin-like transcript 6 (ILT-6), and leukocyte immunoglobulin-like receptor 4 (LIR-4) is a protein that in humans is encoded by the LILRA3 gene located within the eukocyte receptor complex on chromosome 19q13.4. Unlike many of its family, LILRA3 lacks a transmembrane domain, which contains 4 Ig-like C2-type (immunoglobulin-like) domains. LILRA3 acts as soluble receptor for class I MHC antigens. At the same time,LILRA3 can bind both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Also,LILRA3 can bind with high affinity to the surface of monocytes, leading to abolish LPS-induced TNF-alpha production by monocytes.

This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag. The protein has a calculated MW of 48.7 kDa. The protein migrates as 65-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spécification

Spécification

AAH28208.1
HEK293
Human
48.7 kDa
200 µg
Gly 24 - Glu 439
LILRA3,ILT6,LIR4,CD85e
Precision Avi
PBS, pH7.4
Less than 1.0 EU / µg by the LAL method.
MABSol™ Biotin Labeled Proteins
Powder
>95% as determined by reduced SDS-PAGE
Biotinylated Human LILRA3, His,Avitag (LI3-H82E0) is expressed from human 293 cells (HEK293). It contains AA Gly 24 - Glu 439 (Accession # AAH28208.1).
-20°C
LILRA3
His Tag and Avi Tag
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