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CD11b Monoclonal Antibody (M1/70), Functional Grade, eBioscience™, Invitrogen™
Description
The M1/70 MAb reacts with mouse CD11b, the 165-170 kDa integrin alphaM. CD11b non-covalently associates with CD18 to form alphaMbeta2 integrin (Mac-1) and binds to CD54 (ICAM-1), C3bi, and fibrinogen. Mac-1 is expressed by macrophages, NK cells, granulocytes, activated lymphocytes and mouse B-1 cells in the peritoneal cavity. M1/70 is also cross-reactive to human CD11b, and can be used for the detection of this antigen on human peripheral blood monocytes, granulocytes, and a subset of NK cells. Through interactions with its ligands, CD11b participates in adhesive cell interactions.
Spécification
Spécification
| Antigène | CD11b |
| Applications | Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Neutralization |
| Classification | Monoclonal |
| Clone | M1/70 |
| Concentration | 1 mg/mL |
| Conjugué | Functional Grade |
| Formule | PBS with no preservative; pH 7.2 |
| Expression | ITGAM |
| Numéro d’ordre du gène | P05555 |
| Alias de gène | antigen CD11b (p170); antigen CD11b (p170); macrophage antigen alpha polypeptide; CD11 antigen-like family member B; CD11b; CD11B (p170); CD11b/CD18; cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component 3 receptor 3 subunit; complement component receptor 3 alpha-a; complement receptor type 3; CR3; CR-3 alpha chain; CR3A; F730045J24Rik; integrin alpha M; integrin alpha-M; integrin subunit alpha M; integrin, alpha M; integrin, alpha M (complement component 3 receptor 3 subunit); Itgam; Leukocyte adhesion receptor MO1; leukocyte integrin alpha-M chain; Ly-40; MAC1; Mac-1; Mac-1 alpha; Mac-1 alpha (Mac1A); MAC-1 alpha subunit; MAC1A; Mac-1a; macrophage antigen alpha; macrophage antigen alpha polypeptide; MGC117044; MO1A; Neutrophil adherence receptor; neutrophil adherence receptor alpha-M subunit; SLEB6; unnamed protein product |
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