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Invitrogen™ CD138 (Syndecan-1) Monoclonal Antibody (MI15), APC, eBioscience™, Invitrogen™
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Code produit 17121672
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100 Tests
25 Tests
Conditionnement:
100 pièces
25 pièces
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17121672 100 Tests 100 pièces
17111672 25 Tests 25 pièces
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Code produit 17121672 Fournisseur Invitrogen™ Code fournisseur 17138842

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Mouse Monoclonal Antibody

Description: This MI15 monoclonal antibody reacts with human CD138, also known as syndecan-1. CD138 is a transmembrane protein containing chondroitin sulfate and heparin sulfate moieties responsible for binding to the extracellular matrix components. CD138 is not expressed by mature B cells but is present on pre-B cells and the finally differentiated plasma cells. Applications Reported: This MI15 antibody has been reported for use in flow cytometric analysis. Applications Tested: This MI15 antibody has been pre-diluted and tested by flow cytometric analysis of stimulated normal human peripheral blood cells. This may be used at 5 μL (0.25 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser

CD138 (syndecan 1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes. CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury. It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells. Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics. Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.
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Spécification

Antigène CD138 (Syndecan-1)
Applications Flow Cytometry
Classification Monoclonal
Clone MI15
Concentration 5 μL/Test
Conjugué APC
Formule PBS with BSA and 0.09% sodium azide; pH 7.2
Expression Sdc1
Numéro d’ordre du gène P18827
Alias de gène AA408134; AA409076; CD antigen 138; CD138; CD138 antigen; heparan sulfate proteoglycan fibroblast growth factor receptor; HSPG; sCD138; SDC; Sdc1; soluble CD138; Sstn; syn-1; Synd; SYND1; Synd-1; SYNDECA; syndecan; syndecan 1; syndecan proteoglycan 1; Syndecan1; syndecan-1; synstatin
Symboles de gène(s) Sdc1
Espèces hôtes Mouse
Immunogène U-266 cell line.
Méthode de purification Affinity chromatography
Quantité 100 Tests
État réglementaire RUO
Primaire ou secondaire Primary
Identification génétique (Entrez) 6382
Espèces cibles Human
Contenu et stockage 4°C, store in dark, DO NOT FREEZE!
Type de produit Antibody
Forme Liquid
Isotype IgG1 κ
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