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Invitrogen™ CD147 (soluble) Monoclonal Antibody (MEM-M6/1), Alexa Fluor™ 488
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Code produit 15337394
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Quantité:
100 Tests
Conditionnement:
100 tests
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Code produit Quantité unitSize
15337394 100 Tests 100 tests
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Code produit 15337394 Fournisseur Invitrogen™ Code fournisseur MA518126

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Description

Mouse Monoclonal Antibody

This antibody recognizes an extracellular epitope in the N-terminal Ig domain (D1) of CD147 (Neurothelin), a 50-60 kDa type I transmembrane glycoprotein primarily expressed on all leukocytes, red blood cells, platelets and endothelial cells; it is not expressed by resting lymphocytes. The antibody MEM-M6/1 is a high-affinity antibody capable of binding to unstimulated peripheral blood T cells.

CD147 (basigin, neurothelin, OX-47, 5A11, CE9, M6, EMMPRIN, extracellular matrix metalloproteinase inducer, TCSF, tumour cell-derived collagenase-stimulatory factor) is a 50-60 kDa glycoprotein with multiple glycosylated forms. CD147 is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is also a member of the immunoglobulin superfamily. The highest level of CD147 expression is on metabolically active cells, such as lymphoblasts, inflammatory cells, brown adipocytes and malignant tumor cells. CD147 has multiple functions, including facilitating of cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulation of integrin functions, it plays roles in cell development and activation, fetal development or retinal function.
TRUSTED_SUSTAINABILITY

Spécification

Antigène CD147 (soluble)
Applications Flow Cytometry, Western Blot
Classification Monoclonal
Clone MEM-M6/1
Conjugué Alexa Fluor 488
Formule PBS with 0.2% BSA and 15mM sodium azide
Expression BSG
Numéro d’ordre du gène P35613
Alias de gène 5A11; 5A11 antigen; 5A11/Basigin; 5A11/Basigin-2; 5F7; AI115436; AI325119; Basic immunoglobulin superfamily; basigin; basigin (Ok blood group); Basigin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian); basignin; Basignin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian); blood-brain barrier HT7 antigen; BSG; CD147; CD147 antigen; CE9; Collagenase stimulatory factor; EMMPRIN; Extracellular matrix metalloproteinase inducer; glycoprotein CE9; gp 42; gp42/basigin/OX-47/HT7; HT7; HT-7; HT7 antigen; immunoglobulin gene superfamily member; leukocyte activation antigen M6; Membrane glycoprotein gp42; neurothelin; OK; OK blood group antigen; OX-47 antigen; Ox47R; RPE7; TCSF; tumor cell-derived collagenase stimulatory factor; Unknown (protein for MGC:128392); unnamed protein product; UNQ6505/PRO21383
Symboles de gène(s) BSG
Espèces hôtes Mouse
Immunogène Protein A-CR purified soluble recombinant form of CD147, CD147Rg, which consists of the cDNA coding for the hinge region, CH2-and CH3 domain of human IgG1 (CD147Rg is secreted by transfectants as a dimer).
Méthode de purification Size-exclusion chromatography
Quantité 100 Tests
État réglementaire RUO
Primaire ou secondaire Primary
Identification génétique (Entrez) 682
Espèces cibles Human
Contenu et stockage 4°C, store in dark, DO NOT FREEZE!
Type de produit Antibody
Forme Liquid
Isotype IgG1
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