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CD18 Rat anti-Mouse, BB700, Clone: C71/16, BD Optibuild™

Code produit 15897309
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Quantité:
50 μg
Conditionnement:
1 pièce
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15897309 50 μg 1 pièce
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Code produit 15897309 Fournisseur BD Biosciences Code fournisseur 742102

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Rat Monoclonal Antibody

The C71/16 monoclonal antibody specifically binds to mouse CD18 which is also known as the common β2 chain of LFA-1 (CD11a/CD18, αLβ2 integrin), Mac-1 (CD11b/CD18, αMβ2 integrin), and gp150, 95 (CD11c/CD18, αxβ2 integrin). CD18 is a type I transmembrane glycoprotein. Expression of CD18 is limited to leukocytes, where it is widely distributed in consort with the three integrin α chains (CD11a, CD11b, and CD11c). Among splenocytes, NK cells have the highest density of CD18, and T lymphocytes express a higher density than the remaining cells. The β2 integrins are important mediators of leukocyte-endothelium interactions.

The antibody was conjugated to BD Horizon™ BB700, which is part of the BD Horizon Brilliant™ Blue family of dyes. It is a polymer-based tandem dye developed exclusively by BD Biosciences. With an excitation max of 485 nm and an emission max of 693 nm, BD Horizon BB700 can be excited by the 488 nm laser and detected in a standard PerCP-Cy™5.5 set (eg, 695/40nm filter). This dye provides a much brighter alternative to PerCP-Cy5.5 with less cross laser excitation off the 405 nm and 355 nm lasers.BD Horizon Brilliant™ Blue 700 (BB700) is a dye that was exclusively developed by BD Biosciences as brighter alternative to PerCP-Cy5.5. This dye also has less cross laser excitation off the 405 nm laser, resulting in less spillover into the violet channels compared to PerCP-Cy5.5.  Due to similar excitation and emission properties, BD Horizon BB700 and PerCP-Cy5.5 cannot be used simultaneously.
TRUSTED_SUSTAINABILITY

Spécification

Antigène CD18
Classification Monoclonal
Clone C71/16
Concentration 0.2mg/mL
Conjugué Brilliant Blue 700 (BB700)
Formule Aqueous buffered solution containing ≤0.09% sodium azide.
Alias de gène Itgb2, Integrin beta-2, ITB2, LAD, LCAMB, LFA-1/Mac-1/p150,95 subunit beta
Espèces hôtes Rat
Immunogène Cell membrane glycoproteins from mouse T-cell lymphoma BW5147
Méthode de purification Affinity Purified
Quantité 50 μg
État réglementaire RUO
Primaire ou secondaire Primary
Espèces cibles Mouse
Contenu et stockage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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