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Invitrogen™ CD53 Monoclonal Antibody (1H2C7)
Description
CD53 Monoclonal Antibody for Western Blot, IHC (P), Flow, ELISA
CD53 is a tetraspanin family transmembrane glycoprotein expressed in the lymphoid-myeloid lineage. This molecule has been reported to form complexes with other leukocyte surface proteins such as CD2, CD19, CD21, MHC II, VLA-4 or tetraspanins CD37, CD81 and CD82, thus probably modulating various signaling processes. CD53 is involved in radioresistancy of tumor cells and its triggering has anti-apoptotic effect. In thymus, CD53 is up-regulated in response to positive selection signals during T cell development, and is strongly expressed upon macrophage exposure to bacterial lipopolysaccharide, whereas stimulation of neutrophils results in down-regulation of CD53 expression.
Spécification
Spécification
| Antigène | CD53 |
| Applications | ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Western Blot |
| Classification | Monoclonal |
| Clone | 1H2C7 |
| Concentration | 1 mg/mL |
| Conjugué | Unconjugated |
| Formule | PBS with 0.05% sodium azide |
| Expression | Cd53 |
| Numéro d’ordre du gène | P19397 |
| Alias de gène | AI323659; antigen MOX44 identified by monoclonal antibody MRC-OX44; Cd53; CD53 antigen; CD53 glycoprotein; CD53 molecule; CD53 tetraspan antigen; cell surface antigen; cell surface glycoprotein CD53; Leukocyte antigen MRC OX-44; leukocyte surface antigen CD53; MOX44; OX44; Ox-44; tetraspanin-25; transmembrane glycoprotein; TSPAN25; tspan-25 |
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Nom du produit
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