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Invitrogen™ CDK18/cyclin Y Recombinant Human Protein
This CDK18/cyclin Y Recombinant Human Protein (CDK18: full length, cyclin Y: 2-end) was expressed in insect cells.
Marque: Invitrogen™ A30492
Informations supplémentaires : Poids : 0.10000kg
Description
- This CDK18/cyclin Y recombinant human protein (CDK18: full length, cyclin Y: 2-end) was expressed in insect cells
- CDK18/cyclin Y serine/threonine kinase, or cyclin-dependent kinase 18, belongs to the cdc2/cdkx sub-family of kinases
- It is thought to play a role in terminally differentiated neurons, and contains an N-terminal extension relative to CDC2
- CDK18/cyclin Y is expressed in a variety of human cell lines and tissues
- Elevation in the protein levels of CDK18/cyclin Y in the temporal cortex of Alzheimer's disease relative to control brains has been observed
- It is proposed that CDK18/cyclin Y is a paired helical filaments-associated kinase that modulates tau phosphorylation
- CDK18/cyclin Y recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service
- Validated for use with the Z'-LYTE™ assay
- Available in multiple pack sizes for convenient use
Spécification
| CDK18: AAH11526, CyclinY: NP_659449 | |
| 10 µg | |
| CDK18: Full Length, Cyclin Y: 2 - end | |
| GST Tag | |
| Dry Ice | |
| Kinases & Inhibitors | |
| Liquid | |
| Human |
| 80.5/65.5 kDa | |
| CDKs and CHKs | |
| Yes | |
| Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. | |
| Baculovirus | |
| Recombinant, Active, Catalytic | |
| Kinase Assay |