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Invitrogen™ CDK9 Recombinant Human Protein, Inactive
CDK9 is a member of the cyclin-dependent protein kinase family. CDK9 is closely related to cdc28 and cdc2 and is an important regulator of the cell cycle. Recombinant full-length human CDK9 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Marque: Invitrogen™ PV6304
Code nomenclature Nacres: NA.28
Informations supplémentaires : Poids : 0.01000kg
Description
CDK9 is a component of the multiprotein complex TAK/P-TEFβ. CDK9 can modulate RNA polymerase II-directed transcription by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. CDK9 forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. CDK9 also interacts with the HIV-1 Tat protein which suggested a possible involvement of this protein in AIDS.
- Validated in LanthaScreen™ Kinase Binding Assay
- Protocols available for simple use and optimized performance
- Multiple pack sizes available for convenient use
Spécification
| Enzyme and Protein Activity Assay, Industrial and Applied Science, Kinase Assay, Kinase Biology, Kinase Proteins and Expression Reagents, Pharma and Biopharma, Protein Assays and Analysis, Protein Biology, Target and Lead Identification and Validation | |
| 69.1kDa | |
| Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws. | |
| Human | |
| GST Tag |
| 50mM Tris-HCl pH 7.5, 150mM NaCl, 0.1mM EGTA, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol | |
| 10μg | |
| CDC2L4, C-2k, TAK, PITALRE | |
| Recombinant |