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Invitrogen™ Claudin 5 Monoclonal Antibody (4C3C2), Alexa Fluor™ 488

Artikelnummer. 10237304
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Quantité:
100 μg
Pakningsstørrelse:
1 pièce
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Artikelnummer. Quantité Pakningsstørrelse
10237304 100 μg 1 pièce
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Artikelnummer. 10237304 Leverandør Invitrogen™ Leverandørnr. 352588
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Beskrivelse

Mouse Monoclonal Antibody

Reactivity has been confirmed with rat, human and mouse Claudin-5 using rat lung, mouse kidney, mouse small intestine, mouse lung homogenates, human colon tissue, and CACO-2 human cell line. This antibody reacts specifically with the ~ 22-24 kDa endogenous Claudin-5 protein. Excitation/Peak Emission (nm): 495/519.

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc. Alternatively spliced transcript variants encoding different isoforms have been found.
TRUSTED_SUSTAINABILITY

Tekniske data

Antigène Claudin 5
Applications ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 4C3C2
Concentration 0.5 mg/mL
Conjugué Alexa Fluor 488
Formule PBS with 4mg/mL BSA and 0.1% sodium azide; pH 7.4
Expression CLDN5
Numéro d’ordre du gène O00501, O54942, Q9JKD6
Alias de gène AI854493; AWAL; BEC1; Brain endothelial cell clone 1 protein; claudin 5; claudin 5 (transmembrane protein deleted in velocardiofacial syndrome); claudin-5; claudin-5 protein; Cldn5; CPETRL1; lung-specific membrane protein; MBEC1; TMDVCF; TMVCF; Transmembrane protein deleted in VCFS; transmembrane protein deleted in velocardiofacial syndrome; Unknown (protein for MGC:138054)
Symboles de gène(s) CLDN5
Espèces hôtes Mouse
Immunogène Synthetic peptide derived from the mouse Claudin-5 protein.
Méthode de purification Protein A
Quantité 100 μg
État réglementaire RUO
Primaire ou secondaire Primary
Identification génétique (Entrez) 12741, 65131, 7122
Espèces cibles Human, Mouse, Rat
Contenu et stockage 4°C
Type de produit Antibody
Forme Liquid
Isotype IgG1
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