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EMR1 Polyclonal Antibody, Invitrogen™
Description
Recommended positive controls: Jurkat, Raji, K562, C8D30, NIH-3T3, Raw264.7, C2C12, rat liver. Predicted reactivity: Mouse (86%), Rat (84%), Dog (84%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
EMR1 has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. EMR1 is the human ortholog of murine F4/80 but unlike F4/80, the expression of EMR1 in humans is restricted to eosinophils and is not expressed on macrophage populations.
Spécification
Spécification
| Antigène | EMR1 |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 0.23 mg/mL |
| Conjugué | Unconjugated |
| Formule | PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7 |
| Expression | ADGRE1 |
| Numéro d’ordre du gène | Q14246, Q5Y4N8, Q61549 |
| Alias de gène | ADGRE1; Adhesion G protein-coupled receptor E1; Adhesion G protein-coupled receptor E2; cell surface glycoprotein EMR1; cell surface glycoprotein F4/80; DD7A5-7; egf-like module containing, mucin-like, hormone receptor-like 1; EGF-like module containing, mucin-like, hormone receptor-like sequence 1; EGF-like module receptor 1; EGF-like module-containing mucin-like hormone receptor-like 1; EGF-TM7; Emr1; EMR1 hormone receptor; F4/80; Gpf480; Ly71; lymphocyte antigen 71; TM7LN3 |
| Symboles de gène(s) | ADGRE1 |
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Nom du produit
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