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Description
Antibody detects endogenous levels of total FKBP25.
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
Spécification
Spécification
| Antigène | FKBP3 |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugué | Unconjugated |
| Formule | PBS with 50% glycerol and 0.02% sodium azide |
| Expression | FKBP3 |
| Numéro d’ordre du gène | Q00688, Q62446 |
| Alias de gène | 25 kDa FK506-binding protein; 25 kDa FKBP; 25kDa; FK506 binding protein 3; FK506 binding protein 3, 25kDa; FK506-binding protein 25, T-cell; FK506-binding protein 3; FK506-binding protein 3 (25kD); FKBP25; FKBP-25; Fkbp3; FKBP-3; Immunophilin FKBP25; peptidyl-prolyl cis-trans isomerase FKBP3; PPIase; PPIase FKBP3; rapamycin binding protein; rapamycin-selective 25 kDa immunophilin; Rotamase |
| Symboles de gène(s) | FKBP3 |
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Nom du produit
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