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Invitrogen™ Gemin 3 Polyclonal Antibody
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Code produit 15730111 Tous les produits Thermo Scientific Produits
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Quantité:
100 μL
Conditionnement:
100µL
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15730111 100 μL 100µL
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Code produit 15730111 Fournisseur Invitrogen™ Code fournisseur PA552157

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MAKLKHFHCR VLISTDLTSR GIDAEKVNLV VNLDVPLDWE TYMHRIGRAG RFGTLGLTVT YCCRGEEENM MMRIAQKCNI NLLPLPDPIP SGLMEECVDW DVEVKAAVHT YGIASVPNQP LKKQIQKIER TLQIQKAHGD H Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 84%.

Gemin 3 is a member of the DEAD box protein family which are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD) and are putative RNA helicases. DEAD box proteins such as Gemin 3 are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of DEAD box family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Gemin 3 has an ATPase activity and a component of the survival of motor neurons (SMN) complex. The Gemin 3 protein may play a catalytic role in the function of the SMN complex on RNPs. Diseases associated with Gemin 3 protein dysfunction include spinal muscular dystrophy and muscular atrophy.
TRUSTED_SUSTAINABILITY

Spécification

Antigène Gemin 3
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugué Unconjugated
Formule PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Expression Ddx20
Numéro d’ordre du gène Q9UHI6
Alias de gène component of gems 3; DDX 20; DDX20; DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; DEAD box protein 20; DEAD box protein DP 103; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 20; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 20, 103kD; DEAD/H BOX 20; DEAD-box helicase 20; DEAD-box protein DP103; DKFZP434H052; DP 103; Dp103; GEMIN3; Gemin-3; I79_021005; probable ATP-dependent RNA helicase DDX20; putative ATP-dependent RNA helicase DDX20; regulator of steroidogenic factor 1; ROSF-1; SMN-interacting protein
Symboles de gène(s) Ddx20
Espèces hôtes Rabbit
Immunogène Recombinant protein corresponding to Human Gemin 3. Recombinant protein control fragment (Product #RP-102050).
Méthode de purification Antigen affinity chromatography
Quantité 100 μL
État réglementaire RUO
Primaire ou secondaire Primary
Identification génétique (Entrez) 11218
Espèces cibles Human
Contenu et stockage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Type de produit Antibody
Forme Liquid
Isotype IgG
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