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Invitrogen™ GMPS Polyclonal Antibody
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Code produit 13464347
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Quantité:
100 μL
Unit Size:
100µL
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13464347 100 μL 100µL
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Product Code. 13464347 Supplier Invitrogen™ Supplier No. PA529953

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Description

Rabbit Polyclonal Antibody

Recommended positive controls: A431, H1299, HeLa, HepG2. Predicted reactivity: Mouse (96%), Rat (97%), Zebrafish (85%), Dog (97%), Chicken (91%), Rhesus Monkey (99%), Bovine (97%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Transcription factor which plays a key role in defining the composition of the RNA polymerase II (RNAPII) elongation complex and in modulating the production of mature mRNA transcripts. Acts as an assembly factor to recruit various factors to the RNAPII elongation complex and is recruited to the complex via binding to the transcription elongation factor SUPT6H bound to the C-terminal domain (CTD) of the RNAPII subunit RPB1 (POLR2A). The SUPT6H:IWS1:CTD complex recruits mRNA export factors (ALYREF/THOC4, EXOSC10) as well as histone modifying enzymes (such as SETD2) to ensure proper mRNA splicing, efficient mRNA export and elongation-coupled H3K36 methylation, a signature chromatin mark of active transcription.
TRUSTED_SUSTAINABILITY

Specifications

Antigène GMPS
Applications Western Blot
Classification Polyclonal
Concentration 0.69 mg/mL
Conjugué Unconjugated
Formule 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Expression GMPS
Numéro d’ordre du gène P49915
Alias de gène AA591640; AI047208; Glutamine amidotransferase; GMP synthase; GMP synthase [glutamine-hydrolyzing]; GMP synthetase; GMPS; guanine monophosphate synthase; guanine monophosphate synthetase; guanine monphosphate synthase; guanine monphosphate synthetase; guanosine 5'-monophosphate synthase; MLL/GMPS fusion protein; testicular tissue protein Li 82
Symboles de gène(s) GMPS
Espèces hôtes Rabbit
Immunogène Recombinant protein encompassing a sequence within the center region of human GMP synthase. The exact sequence is proprietary.
Méthode de purification Antigen affinity chromatography
Quantité 100 μL
État réglementaire RUO
Primaire ou secondaire Primary
Identification génétique (Entrez) 8833
Espèces cibles Human
Contenu et stockage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Type de produit Antibody
Forme Liquid
Isotype IgG
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