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ACROBiosystems Human 2B4 / CD244 / SLAMF4 Protein, His Tag

Marque:  ACROBiosystems 2B4-H5224-1MG

Informations supplémentaires : Poids : 0.00001kg

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Code produit. 15845847

  • 3011.14€ / 1mg
Expédition estimée: 17-02-2023
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Description

Description

Natural killer cell receptor 2B4 is also known as NK cell type I receptor protein 2B4 (NKR2B4 or h2B4), SLAM family member 4 (SLAMF4), Signaling lymphocytic activation molecule 4, CD antigen CD244. NKR2B4 / CD244 contains two Ig-like (immunoglobulin-like) domains. CD244 is expressed in spleen, PBL, followed by lung, liver, testis and small intestine. CD244 interacts with CD48. Following phosphorylation, CD244 is able to recruit PTPN11/SHP-2 and SH2D1A/SAP. SLAMF4 modulate other receptor-ligand interactions to enhance leukocyte activation. CD244/2B4 is the only heterophilic receptor of SLAM family.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 23.1 kDa. The protein migrates as 35-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spécification

Spécification

NP_057466
23.1 kDa
1 mg
Cys 22 - Arg 221
CD244,2B4,SLAMF4,NKR2B4,NAIL,h2B4
Unconjugated
PBS, pH7.4
HEK293
Human
Powder
>95% as determined by SDS-PAGE
Human 2B4, His Tag (2B4-H5224) is expressed from human 293 cells (HEK293). It contains AA Cys 22 - Arg 221 (Accession # NP_057466).
-20°C
2B4
His Tag
Less than 1.0 EU / µg by the LAL method.
Immune Checkpoint Proteins
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