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ACROBiosystems Human FGF-21 Protein, His Tag

Marque:  ACROBiosystems FG1-H5243-1mg

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 17256200

  • 2258.12€ / 1mg
Expédition estimée: 17-10-2022
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Description

Description

Fibroblast growth factor 21 (FGF21), which stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression. FGF21 has been shown to protect animals from diet-induced obesity when overexpressed in transgenic mice. It also lowers blood glucose and triglyceride levels when administered to diabetic rodents, suggesting it may exhibit the therapeutic characteristics necessary for effective treatment of diabetes. Treatment of animals with FGF21 results in increased energy expenditure, fat utilisation and lipid excretion. FGF21 is most abundantly expressed in the liver, and also expressed in the thymus at lower levels.

This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 21.3 kDa. The protein migrates as 25-28 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spécification

Spécification

NP_061986.1
>90% as determined by SDS-PAGE.
Human FGF-21, His Tag (FG1-H5243) is expressed from human 293 cells (HEK293). It contains AA His 29 - Ser 209 (Accession # Q9NSA1-1).
-20°C
FGF-21
His Tag
Less than 1.0 EU / µg by the LAL method.
Powder
Human
21.3 kDa
1 mg
His 29 - Ser 209
FGF-21, FGF21
Unconjugated
PBS, pH7.4
HEK293
Cytokines&Growth; Factors
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