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ACROBiosystems Human GITR Ligand / TNFSF18 Protein, Fc Tag
3229.78€
Spécification
Numéro d’adhésion | AAH69319.1 |
---|---|
Poids moléculaire | 41.5 kDa |
Source | Human GITR Ligand, Fc Tag (GIL-H526a) is expressed from human 293 cells (HEK293). It contains AA Gln 50 - Ser 177 (Accession # AAH69319.1). |
Immunogène | Gln 50 - Ser 177 |
Conditions de stockage | -20°C |
Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
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Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
15846837
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ACROBiosystems
GIL-H526A-1MG |
1 mg |
3229.78€
1mg |
Expédition estimée: 30-04-2024 Connectez-vous pour voir le stock disponible |
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Description
Tumor necrosis factor ligand superfamily member 18 (TNFSF18) is also known as Glucocorticoid - induced TNF-related ligand (GITRL or GITR Ligand), Activation - inducible TNF - related ligand (AITRL), which belongs to the tumor necrosis factor family. TNFSF18 is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 / GITRL is up-regulated after stimulation by bacterial lipopolysaccharides (LPS). TNFSF18 Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. TNFSF18 / GITR Ligand is important for interactions between activated T-lymphocytes and endothelial cells. TNFSF18 also mediates activation of NF-kappa-B.
This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 41.5 kDa. The protein migrates as 45-48 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spécification
AAH69319.1 | |
Human GITR Ligand, Fc Tag (GIL-H526a) is expressed from human 293 cells (HEK293). It contains AA Gln 50 - Ser 177 (Accession # AAH69319.1). | |
-20°C | |
GITR Ligand | |
Human | |
50 mM Tris, 100 mM Glycine, pH7.5 | |
HEK293 | |
Immune Checkpoint Proteins |
41.5 kDa | |
Gln 50 - Ser 177 | |
TNFSF18,AITRL,TL6,hGITRL,GITR Ligand | |
Unconjugated | |
Fc Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |