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Gibco™ Human Gremlin-1 Recombinant Protein, PeproTech®
CHO cells Recombinant Protein
Marque: Gibco™ 120-42-500UG
Informations supplémentaires : Poids : 0.16500kg
Description
In Xenopus, Gremlin belongs to a novel gene family that act as BMP antagonists in embryonic explants. The human homolog of Drm/Gremlin (CKTFS1B1) is localized on human chromosome 15q13--> q15. DRM-specific mRNA is expressed in different human tissues, including brain, ovary, intestine and colon. It has been suggested that down-regulation of DRM is associated with tumor progression, and support the hypothesis that human DRM may play an important role during both neuroembryological development and carcinogenesis.Spécification
| O60565 | |
| protein with no preservative | |
| 18.3 | |
| 500 µg | |
| -20°C | |
| <1 EU/µg | |
| Grem1 | |
| Unconjugated | |
| KKKGSQGAIP PPDKAQHNDS EQTQSPQQPG SRNRGRGQGR GTAMPGEEVL ESSQEALHVT ERKYLKRDWC KTQPLKQTIH EEGCNSRTII NRFCYGQCNS FYIPRHIRKE EGSFQSCSFC KPKKFTTMMV TLNCPELQPP TKKKRVTRVK QCRCISIDLD | |
| ≥ 90% by SDS-PAGE gel and HPLC analyses. |
| Functional Assay | |
| 26585 | |
| Human Gremlin-1 | |
| CHO cells | |
| RUO | |
| C15DUPq; Cell proliferation-inducing gene 2 protein; CKTSF1B1; colorectal adenoma and carcinoma 1; CRAC1; CRCS4; Cysteine knot superfamily 1, BMP antagonist 1; DAN domain family member 2; DAND2; Down-regulated in Mos-transformed cells protein; down-regulated in v-mos-transformed cells; Drm; DUP15q; Grem; GREM1; gremlin; gremlin 1; gremlin 1 homolog, cysteine knot superfamily; gremlin 1, cysteine knot superfamily, homolog; gremlin 1, DAN family BMP antagonist; gremlin 1-like protein; gremlin-1; HMPS; HMPS1; IHG-2; Increased in high glucose protein 2; increased in high glucose-2; ld; MPSH; PIG2 | |
| Human | |
| Recombinant | |
| Lyophilized |