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ACROBiosystems Human IL-1 RII / CD121b Protein, His Tag

311.92€ - 2135.39€

Spécification

Numéro d’adhésion NP_004624.1
Poids moléculaire 38.9 kDa
Source Human IL-1 RII, His Tag (IL2-H4226) is expressed from human 293 cells (HEK293). It contains AA Phe 14 - Glu 343 (Accession # NP_004624.1).
Immunogène Phe 14 - Glu 343
Conditions de stockage -20°C
Consulter d'autres spécifications

Produits 2
Code produit Marque Quantité Prix Quantité et disponibilité  
Code produit Marque Quantité Prix Quantité et disponibilité  
15857037
Afficher les documents Détails de la promotion
ACROBiosystems
IL2-H4226-1MG
1 mg
2135.39€
1mg
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Expédition estimée: 11-04-2024
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15847037
Afficher les documents Détails de la promotion
ACROBiosystems
IL2-H4226-100UG
100 μg
311.92€
100µg
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Économisez jusqu'à 
»
Expédition estimée: 11-04-2024
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Description

Description

Interleukin-1 receptor type 2 (IL1R2) is also known as CD121 antigen-like family member B (CDw121b), IL-1 type II receptor, Interleukin-1 receptor type II, belongs to the interleukin-1 receptor family. Two distinct types of IL1 receptors which are able to bind IL1 specifically have been identified, designated as IL1RI (IL1RA) and IL1RII (IL1RB). IL1R2 is non-signaling receptor for IL1A, IL1B and IL1RN, reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. IL1R2 modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 38.9 kDa. The protein migrates as 50-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spécification

Spécification

NP_004624.1
Human IL-1 RII, His Tag (IL2-H4226) is expressed from human 293 cells (HEK293). It contains AA Phe 14 - Glu 343 (Accession # NP_004624.1).
-20°C
IL-1 RII
Human
PBS, pH7.4
HEK293
Bio-Markers and CD Antigens
38.9 kDa
Phe 14 - Glu 343
CD121b,IL1RB,IL1R2,CDw121b
Unconjugated
His Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>98% as determined by SDS-PAGE
Vidéos
FDS
Documents

Documents

Product Certifications