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ACROBiosystems Human IL-5 R alpha / CD125 Protein, His Tag
Marque: ACROBiosystems ILA-H52H4-1MG
Informations supplémentaires : Poids : 0.00001kg
Description
Interleukin-5 receptor subunit alpha (IL5RA) is also known as IL-5 receptor subunit alpha, IL-5R subunit alpha and CD125,which is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and type 5 subfamily.IL5R, a heterodimer of an alpha and a beta subunit, is expressed on eosinophils and basophils. IL5RA / CD125 is the receptor for interleukin-5 (IL5) and the alpha chain can bind to IL5. The WSXWS motif of IL5RA appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.The beta subunit of IL5R is common to the IL3, IL5 and GM-CSF receptors.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 37.7 kDa. The protein migrates as 48-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spécification
NP_000555 | |
1 mg | |
Asp 21 - Glu 335 | |
IL5Ra,CD125 | |
Unconjugated | |
His Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>85% as determined by SDS-PAGE |
37.7 kDa | |
Human IL-5 R alpha, His Tag (ILA-H52H4) is expressed from human 293 cells (HEK293). It contains AA Asp 21 - Glu 335 (Accession # NP_000555). | |
-20°C | |
IL-5 R alpha | |
Human | |
PBS, pH7.4 | |
HEK293 | |
Bio-Markers and CD Antigens |