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ACROBiosystems Human TLR4 Protein, Fc Tag

Marque:  ACROBiosystems TL4-H5253-1mg

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 17266580

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Description

Description

Toll-like receptor 4 (TLR4) is a member of the toll-like receptor (TLR) family and highly conserved receptors that recognize conserved pathogen-associated molecular patterns (PAMPs). TLR4 is expressed on the cell surface on both hematopoietic and nonhematopoietic cells, including endothelial cells], cardiac myocytes, and cells of the central nervous system (CNS). TLR4 has been regarded as the sensing receptor for gram-negative lipopolysaccharide (LPS). Further research indicated that TLR4also binds endogenous molecules produced as a result of tissue injury. Thus, TLR4 represents a key receptor on which both infectious and noninfectious stimuli converge to induce a proinflammatory response.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 95.6 kDa.
Spécification

Spécification

Powder
1 mg
Glu 24 - Lys 631
TLR4/hToll/CD284/Toll-like receptor 4
Unconjugated
HEK293
Human
95.6 kDa
Human TLR4, Fc Tag (TL4-H5253) is expressed from human 293 cells (HEK293). It contains AA Glu 24 - Lys 631 (Accession # O00206-1).
-20°C
TLR4
Fc Tag
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