ACROBiosystems Human TLR4 Protein, Fc Tag
Marque: ACROBiosystems TL4-H5253-1mg
Informations supplémentaires : Poids : 0.00010kg
Toll-like receptor 4 (TLR4) is a member of the toll-like receptor (TLR) family and highly conserved receptors that recognize conserved pathogen-associated molecular patterns (PAMPs). TLR4 is expressed on the cell surface on both hematopoietic and nonhematopoietic cells, including endothelial cells], cardiac myocytes, and cells of the central nervous system (CNS). TLR4 has been regarded as the sensing receptor for gram-negative lipopolysaccharide (LPS). Further research indicated that TLR4also binds endogenous molecules produced as a result of tissue injury. Thus, TLR4 represents a key receptor on which both infectious and noninfectious stimuli converge to induce a proinflammatory response.This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 95.6 kDa.
|Glu 24 - Lys 631|
|TLR4/hToll/CD284/Toll-like receptor 4|
|Human TLR4, Fc Tag (TL4-H5253) is expressed from human 293 cells (HEK293). It contains AA Glu 24 - Lys 631 (Accession # O00206-1).|
|Other Recombinant Proteins|