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ACROBiosystems Human VLDL R Protein, His Tag
362.89€ - 2661.24€
Spécification
Numéro d’adhésion | NP_001018066.1 |
---|---|
Poids moléculaire | 84.0 kDa |
Source | Human VLDL R, His Tag (VLR-H5227) is expressed from human 293 cells (HEK293). It contains AA Gly 28 - Ser 769 (Accession # P98155-2). |
Immunogène | Gly 28 - Ser 769 |
Conditions de stockage | -20°C |
Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
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Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
15887937
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ACROBiosystems
VLR-H5227-1MG |
1 mg |
2661.24€
1mg |
Expédition estimée: 24-05-2024 Connectez-vous pour voir le stock disponible |
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15877937
|
ACROBiosystems
VLR-H5227-100UG |
100 μg |
362.89€
100µg |
Expédition estimée: 24-05-2024 Connectez-vous pour voir le stock disponible |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | ||||
Description
The very-low-density-lipoprotein receptor (VLDL-R) is a lipoprotein receptor that shows considerable similarity to the lowdensity-lipoprotein receptor. VLDL R is a 130 kDa type I transmembrane protein in the LDL receptor family that plays a significant role in lipid metabolism and in nervous system development and function .This receptor has been suggested to be important for the metabolism of apoprotein-E-containing triacylglycerol-rich lipoproteins, such as very-low-densitylipoprotein (VLDL), beta-migrating VLDL and intermediate-density lipoprotein. It is also one of the receptors of reelin, an extracellular matrix protein which regulates the processes of neuronal migration and synaptic plasticity. In humans, the VLDL-R is encoded by the VLDLR gene. A rare neurological disorder first described in the 1970s under the name “disequilibrium syndrome” is now considered to be caused by the disruption of VLDLR gene. The disorder was renamed VLDLR-associated cerebellar hypoplasia (VLDLRCH) after a 2005 study. It is associated with parental consanguinity and found in secluded communities such as the Hutterites. VLDLRCH is one of the two known genetic disorders caused by a disruption of reelin signaling pathway, along with Norman-Roberts syndrome.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 84.0 kDa. The protein migrates as 90-110 kDa under reducing (R) condition (SDS-PAGE) due to different glycosylation.Spécification
NP_001018066.1 | |
Human VLDL R, His Tag (VLR-H5227) is expressed from human 293 cells (HEK293). It contains AA Gly 28 - Ser 769 (Accession # P98155-2). | |
-20°C | |
VLDL R | |
Human | |
PBS, pH7.4 | |
HEK293 | |
Bio-Markers and CD Antigens |
84.0 kDa | |
Gly 28 - Ser 769 | |
VLDLR,RP11-320E16.1,CHRMQ1,FLJ35024,VLDLRCH,VLDL receptor | |
Unconjugated | |
His Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>90% as determined by SDS-PAGE |