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LanthaScreen™ Tb-peIF2a (pSer52) Antibody

LanthaScreen™ Tb-peIF2a (pSer52) Antibody

Marque:  Invitrogen PV4815

Code nomenclature Nacres: NA.41

Informations supplémentaires : Poids : 0.00900kg

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Code produit. 10013574

  • 3354.75€ / 1 pièce

En stock, prêt à être expédié : 1

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Description

Description

The alpha subunit of Eukaryotic initiation factor 2 (eIF2alpha) plays a key regulatory role in protein synthesis. In response to a cellular stress, phosphorylation of eIF2alpha at Ser52 occurs by the EIF2AK family of kinases including PERK (EIF2AK3) and PKR (EIF2AK2) to prohibit the initiation of protein synthesis.
For use in combination with the GFP-EIF2alpha physiological protein substrate (PV4809) to evaluate inhibitors in medium to high throughput screening applications.
Spécification

Spécification

Lanthanide Chelates, Terbium (Tb)
Terbium-labeled peIF2a (pThr46) antibody in HEPES buffered saline. Store at -20°C.
Lanthanide Chelates
LanthaScreen®
Hu
Dry Ice
Biochemical Kinase Assays, Drug Discovery and Development, Kinase Biology, Pharma and Biopharma, Target and Lead Identification and Validation
Tb (Terbium), lanthanide chelates
25μg
–20°C
Primary
Serine/threonine kinase
340⁄490, 520
Tb (Terbium)
Human
End Point
Ser/Thr Kinases
0.47mg/mL
Liquid
RUO, For research use only
Primary
1 Each
Vidéos
Documents

For Research Use Only. Not for use in diagnostic procedures.