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Description
Immunogen sequence: PSTSSRLEHF VAILHKCFDS PWTTRALSET VAEQSVRPLK LSKSKILLSS SGCSADIDSG KQSLPYPQPG LESAGIESPT SSVLDKKEGE QAKAIFEKVK RFRMHVEQKD Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.
Non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. Channel activity requires LRRC8A plus at least one other family member (LRRC8B, LRRC8C, LRRC8D or LRRC8E); channel characteristics depend on the precise subunit composition.
Spécification
Spécification
| Antigène | LRRC8B |
| Applications | Immunohistochemistry (Paraffin), Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.2 mg/mL |
| Conjugué | Unconjugated |
| Formule | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Expression | LRRC8B |
| Numéro d’ordre du gène | Q6P9F7 |
| Alias de gène | KIAA0231; leucine rich repeat containing 8 family member B; leucine rich repeat containing 8 family, member B; leucine-rich repeat containing 8 family member B; leucine-rich repeat-containing protein 8B; LRRC8B; T cell activation leucine repeat rich protein; TALRRP; TA-LRRP; T-cell activation leucine repeat-rich protein; UNQ6413/PRO21207; Volume-regulated anion channel subunit LRRC8B |
| Symboles de gène(s) | LRRC8B |
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Nom du produit
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