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Invitrogen™ MEK6 Polyclonal Antibody
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Code produit 13472687
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Quantité:
100 μL
Conditionnement:
100µL
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Code produit Quantité unitSize
13472687 100 μL 100µL
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Code produit 13472687 Fournisseur Invitrogen™ Code fournisseur PA528572

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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, HeLa, HepG2, Molt-4. Predicted reactivity: Mouse (97%), Rat (97%), Zebrafish (88%), Xenopus laevis (93%), Rhesus Monkey (100%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

MKK6 (MEK6, MAP2K6) is a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. Tissue specificity: Isoform 2 is only expressed in skeletal muscle. Isoform 1, on the other hand, is found in skeletal muscle, heart, and in lesser extent in liver or pancreas.
TRUSTED_SUSTAINABILITY

Spécification

Antigène MEK6
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.31 mg/mL
Conjugué Unconjugated
Formule 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Expression MAP2K6
Numéro d’ordre du gène P52564, P70236
Alias de gène Dual specificity mitogen-activated protein kinase kinase 6; MAP kinase kinase 6; MAP2K6; MAPK/ERK kinase 3; MAPK/ERK kinase 6; MAPKK 3; MAPKK 6; MAPKK3; MAPKK6; MEK 3; MEK 6; MEK3; MEK6; mitogen activated protein kinase kinase 6; mitogen-activated protein kinase kinase 6; MKK3; MKK6; PRKMK3; Prkmk6; protein kinase, mitogen activated, kinase 6; protein kinase, mitogen-activated, kinase 6 (MAP kinase kinase 6); SAPK kinase 2; SAPK kinase 3; SAPKK2; SAPKK-2; SAPKK3; SAPKK-3; SKK3; Stress-activated protein kinase kinase 3
Symboles de gène(s) MAP2K6
Espèces hôtes Rabbit
Immunogène Recombinant protein encompassing a sequence within the center region of human MEK6. The exact sequence is proprietary.
Méthode de purification Antigen affinity chromatography
Quantité 100 μL
État réglementaire RUO
Primaire ou secondaire Primary
Identification génétique (Entrez) 26399, 5608
Espèces cibles Human, Mouse
Contenu et stockage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Type de produit Antibody
Forme Liquid
Isotype IgG
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