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![Invitrogen™ Human MET (cMET) [Y1235D], GST Tag Recombinant Protein 10 μg](https://assets.fishersci.com/TFS-Assets/LSG/product-images/Cell_Bio_Rec_Prot_Invitrogen_Vial.jpg-650.jpg)
Invitrogen™ Human MET (cMET) [Y1235D], GST Tag Recombinant Protein
Human MET (cMET) [Y1235D], GST Tag Recombinant Protein
Marque: Invitrogen™ A33505
Informations supplémentaires : Poids : 0.01000kg
Description
- This MET (cMET) Y1235D recombinant human protein (956-end) was expressed in insect cells
- MET receptor tyrosine kinase is a proto-oncogene that encodes a transmembrane growth factor receptor
- MET is widely expressed in the kidney, brain, lung, skin, and embryonic tissue
- Hepatocyte growth factor (HGF) binds to MET and activates its tyrosine kinase activity
- MET is overexpressed and activated in a variety of human cancers including pancreatic, colon, gastric, cervical and ovarian cancers
- It has also been shown to be involved in tumor cell migration and invasion
- MET (Y1235D) is one of the native mutant forms of MET
- MET (cMET) Y1235D recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service
- Validated for use with the Z'-LYTE™ assay
- Available in multiple pack sizes for convenient use
Spécification
| NP_000236.2 | |
| 75.4 kDa | |
| METs (HGFRs) | |
| Human | |
| GST Tag | |
| Dry Ice | |
| Kinases & Inhibitors | |
| Liquid |
| Kinase Assay | |
| 10 μg | |
| aa 956 - 1390 | |
| Recombinant | |
| Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol | |
| Baculovirus | |
| Recombinant, Active, Cytoplasmic, Mutant |