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Invitrogen™ MET (cMET) Y1235D Recombinant Human Protein
This MET (cMET) Y1235D Recombinant Human Protein (956-end) was expressed in insect cells.
Marque: Invitrogen™ A33505
Informations supplémentaires : Poids : 0.01000kg
Description
- This MET (cMET) Y1235D recombinant human protein (956-end) was expressed in insect cells
- MET receptor tyrosine kinase is a proto-oncogene that encodes a transmembrane growth factor receptor
- MET is widely expressed in the kidney, brain, lung, skin, and embryonic tissue
- Hepatocyte growth factor (HGF) binds to MET and activates its tyrosine kinase activity
- MET is overexpressed and activated in a variety of human cancers including pancreatic, colon, gastric, cervical and ovarian cancers
- It has also been shown to be involved in tumor cell migration and invasion
- MET (Y1235D) is one of the native mutant forms of MET
- MET (cMET) Y1235D recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service
- Validated for use with the Z'-LYTE™ assay
- Available in multiple pack sizes for convenient use
Spécification
NP_000236.2 | |
10 µg | |
aa 956 - 1390 | |
GST Tag | |
Insect | |
Liquid | |
Human |
75.4 kDa | |
METs (HGFRs) | |
Yes | |
Dry Ice | |
Recombinant, Active, Cytoplasmic, Mutant | |
Kinase Assay |