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Minocycline hydrochloride, Tocris Bioscience™
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Quantité:
50 mg
Description
Minocycline hydrochloride is a tetracycline antibiotic. Displays neuroprotective, antiapoptotic, anti-inflammatory and antimicrobial effects. Acts as a matrix metalloproteinase (MMP) inhibitor; attenuates disease severity in mouse models of multiple sclerosis. Orally active and brain penetrant. Allows formation of extended pluripotent stem (EPS) cells in combination with CHIR 99021 (Cat.No. 4423), (S)-(+)-Dimethindene maleate (Cat.No. 1425) and human leukemia inhibitory factor.
For more information about how Minocycline hydrochloride may be used, see our protocol: Generation and Propagation of EPS cells (LCDM Cocktail) .
Spécification
| Nom chimique ou matériau | Minocycline hydrochloride |
| CAS | 13614-98-7 |
| Formule moléculaire | C23H28ClN3O7 |
| Numéro MDL | MFCD00083669 |
| Quantité | 50 mg |
| Synonyme | minocycline hydrochloride, minocycline hcl, minomycin, minocin, minocycline chloride, arestin, vectrin, minomax, periocline, tri-mino |
| Clé InChI | KDLQIOPKJDNQIM-WUURTAMISA-N |
| SMILES | [H+].[Cl-].CN(C)[C@H]1[C@@H]2C[C@@H]3CC4=C(C=CC(O)=C4C(O)=C3C(=O)[C@]2(O)C(=O)\C(=C(\N)O)C1=O)N(C)C |
| Nom IUPAC | hydrogen (2Z,4S,4aS,5aR,12aS)-2-[amino(hydroxy)methylidene]-4,7-bis(dimethylamino)-10,11,12a-trihydroxy-1,2,3,4,4a,5,5a,6,12,12a-decahydrotetracene-1,3,12-trione chloride |
| Poids moléculaire (g/mol) | 493.94 |
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