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ACROBiosystems Mouse Fc gamma RI / CD64 Protein, His Tag (BLI verified)

BLI verified Protein

Marque:  ACROBiosystems CD4-M5227-100UG

Informations supplémentaires : Poids : 0.00001kg

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Code produit. 15876197

  • 282.47€ / 100µg
Date d’expédition estimée: 05-01-2022

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Description

Description

Receptors that recognize the Fc portion of IgG are divided into three groups designated Fc gamma RI, RII, and RIII, also known respectively as CD64, CD32, and CD16. Fc gamma RI binds IgG with high affinity and functions during early immune responses. Fc gamma RII and RIII are low affinity receptors that recognize IgG as aggregates surrounding multivalent antigens during late immune responses. High affinity immunoglobulin gamma Fc receptor I is also known as FCGR1A, FCG1, FCGR1, CD64 and IGFR1, is a type of integral membrane glycoprotein that binds monomeric IgG-type antibodies with high affinity, which belongs to the immunoglobulin superfamily or FCGR1 family. FCGR1A / CD64 contains 3 Ig-like C2-type (immunoglobulin-like) domains. CD64 is constitutively found on only macrophages and monocytes, but treatment of polymorphonuclear leukocytes with cytokines like IFNγ and G-CSF can induce CD64 expression on these cells.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 32.3 kDa. The protein migrates as 40-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spécification

Spécification

NP 034316.1
HEK293
Mouse
32.3 kDa
100 µg
Glu 25 - Pro 297
FCGR1A,FCG1,FCGR1,IGFR1,CD64,CD64A,FCRI
Unconjugated
PBS, pH7.4
Less than 1.0 EU / µg by the LAL method.
MABSol™ Fc Receptors
Powder
>95% as determined by SDS-PAGE
Mouse CD64, His Tag (CD4-M5227) is expressed from human 293 cells (HEK293). It contains AA Glu 25 - Pro 297 (Accession # P26151-1).
-20°C
Fc gamma RI / CD64
His Tag
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