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Invitrogen™ MRP1 Polyclonal Antibody
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Code produit 10078009
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Quantité:
400 μL
Conditionnement:
100µg
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Code produit Quantité unitSize
10078009 400 μL 100µg
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Code produit 10078009 Fournisseur Invitrogen™ Code fournisseur PA513543

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Description

Rabbit Polyclonal Antibody

This antibody is predicted to react with bovine, mouse and non-human primate based on sequence homology.

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutathione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing by exon deletion results in several splice variants but maintains the original open reading frame in all forms.
TRUSTED_SUSTAINABILITY

Spécification

Antigène MRP1
Applications Flow Cytometry, Western Blot
Classification Polyclonal
Concentration 2 mg/mL
Conjugué Unconjugated
Formule PBS with 0.09% sodium azide; pH 7.4
Expression ABCC1
Numéro d’ordre du gène P33527
Alias de gène ABC29; ABCC; Abcc1; Abcc1a; Abcc1b; ATP binding cassette subfamily C member 1; ATP-binding cassette sub-family C ( CFTR/MRP) member 1a; ATP-binding cassette sub-family C member 1; ATP-binding cassette transporter variant ABCC1delta-ex13; ATP-binding cassette transporter variant ABCC1delta-ex13&14; ATP-binding cassette transporter variant ABCC1delta-ex25; ATP-binding cassette transporter variant ABCC1delta-ex25&26; ATP-binding cassette, subfamily C (CFTR/MRP), member 1; ATP-binding cassette, sub-family C (CFTR/MRP), member 1; ATP-binding cassette, sub-family C (CFTR/MRP), member 1a; ATP-binding cassette, sub-family C (CFTR/MRP), member 1b; Avcc1a; DKFZp686N04233; DKFZp781G125; Glutathione-S-conjugate-translocating ATPase ABCC1; GS-X; leuk; leukotriene C(4) transporter; LTC4 transporter; Mdrap; MRP; Mrp1; multidrug resistance protein 1; multidrug resistance-associated protein 1; multiple drug resistance-associated protein
Symboles de gène(s) ABCC1
Espèces hôtes Rabbit
Immunogène KLH conjugated synthetic peptide between 1247-1275 amino acids from the C-terminal region of human ABCC1.
Méthode de purification Ammonium sulfate precipitation, Size-exclusion - Dialysis
Quantité 400 μL
État réglementaire RUO
Primaire ou secondaire Primary
Identification génétique (Entrez) 4363
Espèces cibles Human
Contenu et stockage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Type de produit Antibody
Forme Liquid
Isotype IgG
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