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Invitrogen™ Phospho-DAPK1 (Ser308) Monoclonal Antibody (DKPS308)

Description
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
DAPK1 is a large, calmodulin-dependent kinase involved in gamma-interferon induced programmed cell death and is a potential tumor suppressor. DAPK1 is involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and authophagy. It regulates both type I apoptotic and type II autophagic cell death signal, depending on the cellular setting. Type I apoptotic cell death is caspase-dependent, type II authophagic cell death is caspase-independent. DAPK1 phosphorylates PIN1 resulting in inhibition of its catalytic activity, nuclear localization, and cellular function. It also phosphorylates TPM1, STX1A, PRKD1, BECN1, TSC2, RPS6, MYL9, and DAPK3.
Spécification
Spécification
| Antigène | Phospho-DAPK1 (Ser308) |
| Applications | ELISA, Immunoprecipitation, Western Blot |
| Classification | Monoclonal |
| Clone | DKPS308 |
| Concentration | 2.2 mg/mL |
| Conjugué | Unconjugated |
| Formule | PBS with 15mM sodium azide; pH 7.4 |
| Expression | DAPK1 |
| Numéro d’ordre du gène | P53355, Q80YE7 |
| Alias de gène | D13Ucla1; DAP kinase 1; DAPK; DAPK1; DAP-Kinase; death associated protein kinase 1; death-associated protein kinase 1; DKFZp781I035; OTTHUMP00000216193 |
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Nom du produit
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