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Invitrogen™ Phospho-EpoR (Tyr456) Polyclonal Antibody
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Code produit 16682575
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Quantité:
100 μL
Conditionnement:
100µL
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16682575 100 μL 100µL
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Code produit 16682575 Fournisseur Invitrogen™ Code fournisseur PA5106139

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of Epo-R only when phosphorylated at Tyr456.

EpoR encodes the erythropoietin receptor, which belongs to the cytokine receptor family. When erythropoietin binds to this receptor, it activates the Jak2 tyrosine kinase, which in turn activates various intracellular pathways including Ras/MAP kinase, phosphatidylinositol 3-kinase, and STAT transcription factors. The stimulated erythropoietin receptor plays a role in the survival of erythroid cells. Defects in this gene may result in erythroleukemia and familial erythrocytosis. Dysregulation of this gene may also affect the growth of certain tumors. Multiple transcript variants are produced as a result of alternate splicing. Diseases associated with EPOR include Erythrocytosis, Familial, 1 and Erythroleukemia.
TRUSTED_SUSTAINABILITY

Spécification

Antigène Phospho-EpoR (Tyr456)
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugué Unconjugated
Formule PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Expression EPOR
Numéro d’ordre du gène P14753, P19235, Q07303
Alias de gène EPO R; EPOR; EPO-R; Erythropoietin receptor; pEpoR
Symboles de gène(s) EPOR
Espèces hôtes Rabbit
Immunogène A synthesized peptide derived from human EPOR(Accession P19235), corresponding to amino acid residues around phosphorylated Tyr456.
Méthode de purification sequential chromatography
Quantité 100 μL
État réglementaire RUO
Primaire ou secondaire Primary
Identification génétique (Entrez) 13857, 2057, 24336
Espèces cibles Human, Mouse, Rat
Contenu et stockage -20°C
Type de produit Antibody
Forme Liquid
Isotype IgG
Afficher plus Visa mindre
Produkttitel
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